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“The Rose Sheet”

E’shee Clinical Esthetic joins an emerging segment within anti-aging cosmeceuticals with its peptidepowered skin-care products that deliver results by activating stem cells in skin.

The Somerville, N.J.-based firm says it is the first personal-care company to use acidic fibroblast growth factor, or FGF-1, a heparin-binding protein involved in tissue repair [...]]]>

June 28, 2010

“The Rose Sheet”

E’shee Clinical Esthetic joins an emerging segment within anti-aging cosmeceuticals with its peptidepowered skin-care products that deliver results by activating stem cells in skin.

The Somerville, N.J.-based firm says it is the first personal-care company to use acidic fibroblast growth factor, or FGF-1, a heparin-binding protein involved in tissue repair and wound healing.

Although it characterizes FGF-1 as “stem cell technology,” the company is quick to note online that its products “aren’t about putting embryonic stem cells in a jar and slathering them all over your face. Instead the technology focuses on using polypeptides and enzymes to ‘awaken’ the body’s own reservoir of epidermal stem cells to rejuvenate the skin.”

In June 22 interview, E’shee founder Nataly Giter acknowledged that “stem cells make some people nervous.” However, “the customer is also more educated now. It is not about taking someone’s and applying them to yourself, it’s about repairing [damage to] your own cells from aging and pollution.” With aging, the function of stem cells in skin repair is less efficient. “If stem cells are not getting signals, there are not repairs,” Giter explained. “FGF-1 delivers the signal to start rejuvenating.” As opposed to Botox and other injectable fillers, “our products trigger the body to do its job. It doesn’t artificially fill the wrinkles,” said Giter.

Giter learned of FGF-1 from Ohio University professor Dr. Ing-Ming Chiu, who was first to clone the human FGF-1 gene. Chiu’s research has explored the growth factor’s use to address neurological damage and broken capillaries, as well as skin. Giter got involved about 10 years ago and started laying the groundwork for a line of skin-care products.

Fibroblast growth factors are signaling molecules that play important roles in the processes of cell proliferation and differentiation. FGF-1 interacts with multiple receptors to not only revitalize the epidermis – as is possible with epidermal growth factor, or EGF, which many cosmetics manufacturers use, according to E’shee – but also to stimulate underlying fibroblast cells that produce collagen, elastin and hyaluronic acid.

According to the company, use of its products that contain FGF-1 makes “skin cells grow 10 to 20 times faster than if using any other skin-care products.”

Firm Offers Six-Ampoule Set

E’shee’s collection consists of six products that sell in spas and physicians’ offices, as well as at EsheeEsthetic.com. The brand promises “wrinklefree skin within 30 days.”

Gene Therapy Serum for Cellular Repair is “the only product on the market that combines hyaluronic acid and FGF-1,” the firm notes. The results are firmer skin with increased volume, disappearance of fine lines and a reduction in deep wrinkles. Giter says the serum also “cuts off healing time by up to 60 percent after plastic surgery.” A 0.34-oz ampoule is $179.

Giter is providing training seminars to physicians and spa technicians on how to use the product, as well as how to use it in combination with other products in the company’s stable.

Gene Therapy Serum for Cellular Repair and Bota Therapy Concentrate Serum ($189) work together to deliver “lifting action” and improve skin quality, Giter said. Bota Therapy awards a nearly 30 percent reduction in the appearance of “dynamic” wrinkles after 30 days of use, decreasing facial lines and wrinkles by up to 68 percent in 45 to 60 days, according to E’shee.

Other offerings include Serum Hydra Gold, which mimics a facial and includes flecks of gold leaf, and Serum Vitalizing “C” which facilitates the transfer of Vitamin C into cells to reduce fine lines, wrinkles, age spots and sagging skin. Each is priced at $119.

Serum Intensive Brightening, also $119, is an “intensive booster treatment” that corrects pigmentations spots and skin discoloration from acne, the firm says. The antioxidant product contains 15 percent L-ascorbic acid and 1.5 percent m-Transexamic Acid.

– Suzanne Blecher (s.blecher@elsevier.com)

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Fri, 18 Jun 2010, 18:01:45 EDT Edited by Liisa Sullivan

SOMERVILLE, N.J., June 18 (SEND2PRESS NEWSWIRE) — E’shee Skin Care products are the result of a careful collaboration of skin care professionals, doctors and chemists; these revolutionary [...]]]>

A New Era in Anti-Aging: E’shee Clinical Esthetic Launches Advanced Technology Skin Care Product Line

Fri, 18 Jun 2010, 18:01:45 EDT
Edited by Liisa Sullivan

SOMERVILLE, N.J., June 18 (SEND2PRESS NEWSWIRE) — E’shee Skin Care products are the result of a careful collaboration of skin care professionals, doctors and chemists; these revolutionary new products are the next step in skin care.

Specifically formulated to use very small molecular structures to maximize penetration and dispersion of their beneficial properties, these patented skin care products are redefining “state of the art.”

In several of E’shee’s skin care products, the human Acidic Fibroblast Growth Factor, also known as FGF-1 (or aFGF), is included in the formula. FGF-1 stimulates stem cell growth and produces never-seen-before end results. And, E’shee is proud to be the only skin care line in the U.S. to use this ingredient in their skin care products.

According to E’shee’s president, Nataly Giter, “FGF 1 is the best cosmetic component to trigger the body’s natural resources to self-repair.”

The “Best in Class” of E’shee’s six set ampoule collection is The Gene Therapy Serum for Cellular Repair. It regenerates cell structure by giving cells the orders for revitalization. It is the only product on the market that combines non-cross-linked Hyaluronic acid and gene therapy via FGF-1 to rejuvenate damaged or aging skin. Clinical tests show perceived improvement against skin’s visual aging.

This key ingredient plays a very important role in tissue repair and also wound healing. Based on E’shee’s research, FGF-1 peptide can transfer different messages to:
* FGFR-2 – rejuvenates fibroblast cells to produce new collagen, hyaluronic acid and elastin;
* KGFR – rejuvenates the epidermal cells; and
* FGF-7 – rejuvenates hair follicle to produce new hair.

Other growth factors used in skin care products such as EGF (Epidermal Growth Factor) only rejuvenate the epidermis; they do not simulate the production of collagen, hyaluronic acid and elastin like FGF-1 and the aging process will remain or get worse.

FGF-1 works as a catalyst and skin cells grow 10 to 20 times faster when compared to other professional skin care products.

About E’shee Clinical Esthetic:
Launched in 2009 by Nataly Giter, a skin care professional who has worked with many of the world’s best products, Giter sought to develop more effective skin care products. Through research and practical experience, she learned about the ingredients that work best and became associated with Dr. Chiu, a professor from Ohio University. Dr. Chiu is the first global pioneer to clone human FGF-1 gene.

Together with Dr. Chiu, his team of chemists and their combined connections to industry professionals, they utilized FGF 1 to create this anti-aging extraordinary product line.

For more information, visit: www.esheeesthetic.com.

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Radio frequency is an innovative technological, which increases the temperature in the tissues at a selected depth. According to the operator’s needs, radio frequency acts on the surface or in depth, [...]]]>

What is it?

Radio frequency is an electromagnetic energy flow which goes through the tissues, inducing a uniform heating in the treated area.

What does it do?

Radio frequency is an innovative technological, which increases the temperature in the tissues at a selected depth. According to the operator’s needs, radio frequency acts on the surface or in depth, involving the deeper skin layers, (dermis and hypodermis) and protecting those superficial from the thermal damage.

What is it used for?

Smooths tissues and reduces the flabbiness, inducing a sort of not surgical lifting, with a real reshaping and a visible skin rejuvenation meets localized fat and cellulite, heating the selective areas and stimulating the cellular metabolic activity
increasing of blood and lymph microcirculation induced by the vasodilatation and a better oxygen supply, exhaust toxin and waste.

Contraindications:

• Pregnancy and lactation
• Epilepsy
• Open Wounds
• Heart disease or pacemaker
• Skin Disease
• High Fever
• Serious capillary vessel enlargement
• Serious form of diabetes

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