Created in collaboration with skin care professionals, doctors and chemists, E'shee Clinical Skin Care Products are the next step in skin care.

The advanced active ingredients that we use in our serums are specially formulated to use patented molecular structures to maximize penetration and dispersion of their beneficial properties. This reformulation is the state of art in skin care products. Each single serum produces remarkable results. If used in a combination, they compliment each other and enhance the outcome. E'shee Clinical Ampoule Collection covers all aspects of skin aging: it repairs on genetic level, nourishes on molecular level and protects on cellular level.

E'shee Clinical Esthetic goes one step further by including Acidic Fibroblast Growth Factor, also known as FGF 1, in several of the products. FGF 1 stimulates stem cell response producing effects that have not been seen before.

E'shee Clinical Esthetic, Technology
Stem Cell Technology in skin care products.

E'shee Clinical Esthetic, Technology The Future of Skin Rejuvenation. These uber-sophisticated skin potions really do make you look younger... Before you go crazy about the term "Stem Cells" (the two most controversial words in science), here's something you need to know: These new topical creams aren't about putting embryonic stem cells in a jar and slathering them all over your face. Instead the technology focuses on using polypeptides and enzymes to "awaken" the body's own reservoir of epidermal stem cells to rejuvenate the skin and make you look younger - a lot younger! The fact is, skin is the largest repository of stem cells in the human body ... Here's what Richard Wells, Ph.D., told me: ... As we age, stem-cell utilization for skin repair is less efficient. However, the potential that nature has given us to access these endogenous stem-cell reservoirs for skin rejuvenation is quite remarkable. That's why science is seeking to activate the potential of our inherent adult stem-cell reservoirs. In so doing, the practical use of stem-cell technology can provide the consumer with a topical, anti-aging cosmetic formula that simply makes everyone look years younger" ... Stem cells are hot - really, really hot. Imagine new, fresh, "perfect" skin cells, undamaged by age, sun or pollution. E'shee Clinical Esthetic, Technology From: ASA Adjudication on Basic Research LLC

"Human Recombinant Acidic Fibroblast Growth Factor", also names aFGF or FGF 1 in the FGFs family.

E'shee Clinical Esthetic, Technology
FGF 1 pathways

This is our new and most advanced product with high technology from Ohio University. Professor Dr. Chiu is the first global pioneer to clone human FGF 1 gene. Research focuses on the gene-therapy for the medical use, including brain tumor and neural damages. Cooperating with professor Dr. Chiu, our lab created a brand new series using 99% pure FGF 1 peptide, which has the best quality in the world. Fibroblast Growth Factors are key players in the processes of proliferation (cell division) and differentiation (cellular differentiation); A process by which a less specialized cell (stem cells) becomes a more specialized cell type of wide variety of cells and tissues. By triggering the mechanism, FGF can stimulate the process of healing and repairing of the damaged tissue. Based on our research, FGF 1 peptide can transfer different "massages" to FGFR-2 (rejuvenates fibroblast cells to produce new collagen, hyaluronic acid and elastin), KGFR (rejuvenates the epidermal cells) and FGF-7 (rejuvenates hair follicle to produce new hair).

Comparing with other growth factors

Many cosmetic manufacturers use EGF (Epidermal Growth Factor) that only rejuvenates the epidermis, without stimulating the production of collagen, hyaluronic acid and elastin. With the sole use of EGF the aging process will persist or deteriorate.

FGF 1 rejuvenates both: the epidermal cells and the underlying fibroblast cells, which produce collagen, elastin, and hyaluronic acid.

These ingredients are now integrated into our cosmetic products. The testing results show that with regular usage of products which contains FGF 1, the skin cells grow 10-20 times faster than if using any other skin care products. We use aFGF, which not only makes the surface of the skin smoother and more radiant, but also makes the dermal structures stronger. The skin becomes more elastic and firm in about 28 days of the treatment.

Combined with the other advanced active ingredients, we present you the NEW ERA of anti-aging treatment.